期刊
JOURNAL OF DENTAL RESEARCH
卷 82, 期 3, 页码 200-205出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/154405910308200310
关键词
multilevel modeling; hierarchical linear modeling; random coefficients; lifetime cumulative attachment loss; pocket probing depth
Previously, burst and linear theories for periodontal disease progression were proposed based on different but limited statistical methods of analysis. Multilevel modeling provides a new approach, yielding a more comprehensive model. Random coefficient models were used to analyze longitudinal periodontal data consisting of repeated measures (level 1), sites (level 2), teeth (level 3), and subjects (level 4). Large negative and highly significant correlations between random linear and quadratic time coefficients indicated that subjects and teeth with greater-than-average linear change experienced decelerated variation. Conversely, subjects and teeth with lessthan-average linear change experienced accelerated variation. Change therefore exhibited a dynamic regression to the mean at the tooth and subject levels. Since no equilibrium was attained throughout the study, changes were cyclical. When considered as a multilevel system, the linear and burst theories of periodontal disease progression are a manifestation of the same phenomenon: Some sites improve while others progress, in a cyclical manner.
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