期刊
AMERICAN JOURNAL OF PRIMATOLOGY
卷 59, 期 3, 页码 123-128出版社
WILEY-LISS
DOI: 10.1002/ajp.10069
关键词
nonhuman primates; serology; serological survey; health monitoring; viruses
类别
资金
- NCRR NIH HHS [RR00169] Funding Source: Medline
The rhesus macaque breeding colony of the Oswaldo Cruz Foundation (FIOCRUZ) was established in 1932 from a founding stock of 100 animals. This population has remained closed to new animal introductions for almost 70 years. A serologic survey was performed to determine the prevalence of antibodies to selected viruses as a first approach to identifying viral pathogens endemic in this population. Banked serum samples were tested for antibodies to simian immunodeficiency virus (SIV), simian T-lymphotropic virus (STLV), simian type D retrovirus (SRV), cercopithecine herpesvirus type-1 (B virus), rhesus cytomegalovirus (RhCMV), measles virus (MV), and hepatitis A virus (HAV). All samples were negative for antibodies against the simian retroviruses. The overall prevalence of antibodies was 95% for RhCMV, 45% for B virus, 35% for HAV, and 1% for MV. Prevalence was found to vary by age group. (C) 2003 Wiley-Liss, Inc.
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