期刊
HEALTH PSYCHOLOGY
卷 22, 期 2, 页码 223-228出版社
AMER PSYCHOLOGICAL ASSOC
DOI: 10.1037/0278-6133.22.2.223
关键词
HIV; addiction; methadone; risk behavior; adherence
资金
- NIDA NIH HHS [P50-DA09241, R01-DA10851, K21-DA00277] Funding Source: Medline
- NIMH NIH HHS [P01-MH/DA-56826] Funding Source: Medline
This study randomized 90 HIV-seropositive, methadone-maintained injection drug users (IDUs) to an HIV Harm Reduction Program (HHRP+) or to an active control that included harm reduction components recommended by the National AIDS Demonstration Research Project. The treatment phase lasted 6 months, with follow-ups at 6 and 9 months after treatment entry. Patients in both treatments showed reductions in risk behaviors. However, patients assigned to HHRP+ were less likely to use illicit opiates and were more likely to adhere to antiretroviral medications during treatment; at follow-up, they had lower addiction severity scores and were less likely to have engaged in high risk behavior. Findings suggest that enhancing methadone maintenance with an intervention targeting HIV-seropositive IDUs increases both harm reduction and health promotion behaviors.
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