期刊
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
卷 55, 期 2, 页码 181-184出版社
ELSEVIER
DOI: 10.1016/S0939-6411(02)00196-0
关键词
calixarenes; solid lipid nanoparticles; carbohydrates; cryoprotectants; atomic force microscopy
In this note, we report a study of cryoprotectant carbohydrate (glucose, fructose, mannose and maltose) effects on the reconstitution of calixarene based solid lipid nanoparticle (SLN) suspensions after freeze-drying, studied by atomic force microscopy and photon correlation spectroscopy. All carbohydrates tested showed excellent cryoprotection and redispersion properties with the calixarene based SLNs. (C) 2003 Elsevier Science B.V. All rights reserved.
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