期刊
PEDIATRIC RADIOLOGY
卷 33, 期 3, 页码 207-210出版社
SPRINGER-VERLAG
DOI: 10.1007/s00247-002-0828-y
关键词
chiasmatic pilocytic astrocytoma; malignant transformation; diencephalic syndrome; metastatic spread
Chiasmatic gliomas with metastatic spread are rare in children and are usually associated with diencephalic syndrome. They are mostly pilocytic astrocytomas and their transformation to high-grade astrocytomas has never previously been reported in the pediatric population. We report leptomeningeal spread of a chiasmatic pilocytic astrocytoma in a child presenting with diencephalic syndrome. He was treated with chemotherapy and radiation. The tumor recurred with transformation into a high-grade astrocytoma. Radiation therapy may have played a role in transformation of the tumor, but more research is needed to further clarify the biological behavior of this tumor.
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