期刊
TETRAHEDRON LETTERS
卷 44, 期 12, 页码 2485-2487出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(03)00325-3
关键词
bicyclic compounds; cyclizations; cyclopropanes; nitriles; titanium
Here we report an easy synthesis of bicyclic primary cyclopropylamines directly from unsaturated nitriles. The described reaction involves Ti(II)-mediated intramolecular coupling of alkene and nitrile moieties. (C) 2003 Elsevier Science Ltd. All rights reserved.
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