期刊
EUROPEAN JOURNAL OF PHARMACOLOGY
卷 464, 期 2-3, 页码 159-162出版社
ELSEVIER
DOI: 10.1016/S0014-2999(03)01421-3
关键词
formalin test; hyperalgesia; migraine; nitric oxide (NO); pain; tail-flick test
Nitroglycerin is a nitric oxide (NO) donor which activates nuclei involved in nociceptive transmission following systemic administration. The effect of nitroglycerin on the nociceptive threshold was studied in rats by means of two experimental tests that explore different modalities of pain: the tail-flick test and the formalin test. Nitroglycerin induced a significant reduction in the latency of the tail flick 2 and 4 It after its administration. Similarly, formalin-induced pain-related behaviour increased significantly 2 and 4 It after nitroglycerin administration. (C) 2003 Elsevier Science B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据