期刊
TRENDS IN IMMUNOLOGY
卷 24, 期 4, 页码 213-219出版社
ELSEVIER SCI LTD
DOI: 10.1016/S1471-4906(03)00032-2
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- NCRR NIH HHS [R01 RR013601, RR 13601, R01 RR013601-05] Funding Source: Medline
- NHLBI NIH HHS [R01 HL064560-05, R01 HL064560, HL 64560] Funding Source: Medline
The role of gammadelta T cells in adaptive immunity remains uncertain. Recent studies have demonstrated that a unique subset of gammadelta T cells in primates can mount adaptive immune responses during mycobacterial infections. This Review discusses notable similarities and differences in adaptive immune responses between non-peptidespecific gammadelta T cells and peptide-specific up T cells, and discusses both the molecular basis for gammadelta T-cell responses and potential functions of these enigmatic cells.
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