期刊
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
卷 26, 期 4, 页码 347-352出版社
SPRINGER
DOI: 10.1007/BF03345183
关键词
acromegaly; estrogen; contraceptive pill; GH; IGF-I
In some acromegalic patients medical treatment does not succeed in normalizing GH/IGF-I values. Data showing IGF-I suppression in acromegaly by estrogen and by tamoxifen use prompted us to reevaluate the effects of estroprogestins (EP) supplementation on GH/IGF-I levels in acromegalic women resistant or only partially sensitive to medical treatment. Eight active acromegalic women (30-52 yr, 4 with regular menses) entered a prospective open pilot study. Three of them, resistant to medical treatment, were off therapy, the remaining five, partially sensitive, maintained it at the maximally effective dosages throughout the study. Patients were treated with a triphasic pill (ethynil-estradiol 3040-30 mug/day and clesogestrel 50-70-100 mg/day).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据