期刊
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
卷 293, 期 1, 页码 77-86出版社
ELSEVIER GMBH
DOI: 10.1078/1438-4221-00246
关键词
intestinal flora; mucosal immunity; tolerance; inflammatory bowel disease; probiotics
The normal intestinal flora and the mucosal immune system exist in close spatial proximity. A normal structure and function of both very complex systems is required for health and develops in a constant and interactive process. An abnormal host response to the normal intestinal flora leads to chronic intestinal inflammation. Probiotic bacteria may modulate the intestinal flora and the mucosal immune response and are an effective therapy for remission maintenance of ulcerative colitis and pouchitis.
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