期刊
EUROPEAN JOURNAL OF CANCER PREVENTION
卷 12, 期 2, 页码 93-100出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00008469-200304000-00002
关键词
cutaneous malignant melanoma; p53; ultraviolet radiation; UV
类别
资金
- NIAMS NIH HHS [AR02136] Funding Source: Medline
Cutaneous malignant melanoma (CMM) is a life-threatening cancer that can have a poor prognosis with high metastatic potential. Its incidence is rapidly increasing worldwide. Its molecular alterations involve multiple pathways, including those related to p53. Since 1981, more than 380 papers containing the terms 'p53 and melanoma' as key words in the Abstract have been published in the literature. However, in spite of these extensive investigations, a review of p53 and associated genes in CMM is still lacking. To remedy this issue, this review seeks to provide a brief overview of p53 and discuss the genes targeted along its related pathways. (C) 2003 Lippincott Williams Wilkins.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据