期刊
JOURNAL OF PERIODONTOLOGY
卷 74, 期 4, 页码 485-493出版社
AMER ACAD PERIODONTOLOGY
DOI: 10.1902/jop.2003.74.4.485
关键词
alcoholism; cocaine abuse; periodontal attachment loss/etiology; periodontitis/etiology
资金
- NIAAA NIH HHS [AA08195] Funding Source: Medline
- NIDCR NIH HHS [DE10592] Funding Source: Medline
Background: The objective of this study was to examine the effects of alcohol and cocaine misuse on periodontal status in a group of alcohol-dependent patients. Methods: Forty verified alcoholics, either exclusively (n = 10) or with cocaine abuse (n = 30), and a matched comparison group of 25 non-alcoholic subjects, 14 of whom abused cocaine, were entered in the study. All subjects were free from systemic illnesses. Blood levels of gamma glutamyl transpeptidase (GGTP), a liver enzyme indicator of alcohol drinking, were determined. A comprehensive periodontal examination was performed on 6 sites per tooth. The gingival index (GI) and plaque index (PI) were recorded. Attachment levels (AL) were computed as probing depth (PD) plus gingival margin level (GM). Results: No statistically significant differences were noted between the groups for average AL, PD, GM, GI, and PI. In alcoholics, Pearson correlation showed a positive association between GGTP levels and loss of periodontal attachment (P <0.05). A series of regression analyses predicting AL from selected periodontal and demographic factors showed that alcoholics manifest AL by greater increases in GM than non-alcoholics (P <0.07). Severe alcohol use as measured by GGTP >51 iu/l worsens PI (P <0.07), which adversely impacts GM, GI, PD, and ultimately AL. No significant associations were found between cocaine use and AL. Conclusions: The results suggest that persistent alcohol abuse increases periodontitis development by heightening the loss of attachment through recession of gingival margins.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据