期刊
PHYSIOLOGY & BEHAVIOR
卷 78, 期 4-5, 页码 635-640出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0031-9384(03)00040-4
关键词
vestibular; circling; rearing; conditioned taste aversion; locomotor activity
资金
- NIDCD NIH HHS [NIDCD 04607] Funding Source: Medline
- NINDS NIH HHS [T32 NS 7437] Funding Source: Medline
High-strength static magnetic fields are common tools in clinical imaging, but the behavioral effects are not well characterized. Previous studies on rats showed that fields of 7 T or above produced locomotor circling, conditioned taste aversion (CTA) and c-Fos in vestibular nuclei. To determine the generality of the behavioral effects on a smaller species, we subjected restrained or unrestrained mice to 30-min exposures in a 14.1-T field. Mice were given saccharin immediately prior to magnet or sham exposure on 3 consecutive days. All mice exposed to the magnet developed a CTA, and a significant number displayed tight circling and suppression of rearing. Unrestrained mice exhibited larger effects than restrained mice. These effects, similar to the effects in rats, may be the result of a vestibular disturbance caused by the magnetic field. (C) 2003 Elsevier Science Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据