On long-term depression induced by activation of G-protein coupled receptors

In this mini-review I consider the mechanisms by which activation of glutamate and acetylcholine metabotropic receptors can result in the induction of long-term depression. Two regions of the CNS will receive particular attention; the CA1 region of hippocampus and the perirhinal cortex. (C) 2003 Elsevier Science Ireland Ltd and the Japan Neuroscience Society. All rights reserved.