期刊
JOURNAL OF CELL SCIENCE
卷 116, 期 7, 页码 1199-1207出版社
COMPANY BIOLOGISTS LTD
DOI: 10.1242/jcs.00298
关键词
ZP proteins; cuticulin envelope; epithelial morphogenesis; cuticule formation; Drosophila
类别
We have characterised the function of two Drosophila genes, miniature and dusky, that are required for the morphological reorganisation of the apical membrane during wing epidermis differentiation. These genes encode transmembrane proteins containing a ZP (zona pellucida) domain and are homologous to several vertebrate and invertebrate apical matrix components. miniature and dusky are only expressed in tissues secreting a cuticle, and the Min protein localises to the apical membrane during the early stages of cuticle formation. We propose that Min and Dusky form a novel subfamily within the ZP domain proteins and are specifically involved in the interactions between the apical membrane, the cytoskeleton and the forming cuticle.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据