期刊
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
卷 69, 期 4, 页码 2365-2371出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.69.4.2365-2371.2003
关键词
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Collective transcriptional analysis of heat shock response in the hyperthermophilic archaeon Pyrococcus furiosus was examined by using a targeted cDNA microarray in conjunction with Northern analyses. Differential gene expression suggests that P.furiosus relies on a cooperative strategy of rescue (thermosome [Hsp60], small heat shock protein [Hsp20], and two VAT-related chaperones), proteolysis (proteasome), and stabilization (compatible solute formation) to cope with polypeptide processing during thermal stress.
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