期刊
ARTIFICIAL ORGANS
卷 34, 期 11, 页码 1044-1048出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1525-1594.2010.01143.x
关键词
Bioprinting; Regenerative medicine; Tissue engineering; 3D printing; Bioartificial organ
资金
- Basic Research Program for the Korea Science & Engineering Foundation, Korea [2009-0076151, R01-2006-000-11368-0]
- Ministry of Education and Human Resources Development, Republic of Korea
- National Research Foundation of Korea [R01-2006-000-11368-0, 2009-0076151] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Bioprinting is an emerging technology for constructing tissue or bioartificial organs with complex three-dimensional (3D) structures. It provides high-precision spatial shape forming ability on a larger scale than conventional tissue engineering methods, and simultaneous multiple components composition ability. Bioprinting utilizes a computer-controlled 3D printer mechanism for 3D biological structure construction. To implement minimal pattern width in a hydrogel-based bioprinting system, a study on printing characteristics was performed by varying printer control parameters. The experimental results showed that printing pattern width depends on associated printer control parameters such as printing flow rate, nozzle diameter, and nozzle velocity. The system under development showed acceptable feasibility of potential use for accurate printing pattern implementation in tissue engineering applications and is another example of novel techniques for regenerative medicine based on computer-aided biofabrication system.
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