Surgical ablation of retinal angiomatous proliferation

Age-related macular degeneration (AMD) remains the leading cause of visual loss in adults older than 65 years. Retinal angiomatous proliferation (RAP) is a newly recognized manifestation of exudative AMD that has poor natural history and demonstrated resistence to resistence to treatment with conventional laser photocoagulation. A novel surgical technique has been developed in this pilot series that shows promise in the treatment of this subtype of neovascular lesions. Through specific surgical lysis of the feeding arteriole and draining venule of an RAP lesion, improvement in visual acuity has been noted. This has been correlated with resolution of intraretinal edema and flattening of associated pigment epithelia detachment, which was confirmed by fluorescein angiography, optical coherence tomography, and high-speed indo cyanine green angiography. Arc Ophthalmol. 2003;121:558-561.