期刊
CLINICAL RHEUMATOLOGY
卷 22, 期 2, 页码 143-145出版社
SPRINGER-VERLAG
DOI: 10.1007/s10067-002-0679-9
关键词
Crohn's disease; inflammatory bowel disease; myalgia; myositis
类别
A 19-year-old woman presented with pain and tenderness in both calves associated with pyrexia and neutrophil leukocytosis. Gastrocnemius muscle biopsy showed a non-specific lymphocytic myositis and she was found to have positive c-ANCA, in the absence of other evidence of systemic vasculitis. Subsequent investigation of her gastrointestinal tract revealed extensive Crohn's disease. The myositis responded promptly to treatment with prednisolone 0.5 mg/kg. A review of the literature showed that localised calf pain in the setting of Crohn's disease can be caused by non-specific myositis, granulomatous myositis or vasculitis. It is proposed that the ''gastrocnemius myalgia syndrome'' be included in the typical-albeit rare-extraintestinal manifestations that may herald the appearance of inflammatory bowel disease.
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