期刊
CLINICAL MEDICINE
卷 3, 期 3, 页码 285-286出版社
ROY COLL PHYS LONDON EDITORIAL OFFICE
DOI: 10.7861/clinmedicine.3-3-285
关键词
Brenner; caenorhabditis elegans; development; differentiation; Nobel Prize
The recent award of a Nobel Prize to Sydney Brenner crowns an astonishingly distinguished scientific career. He must have come very close to winning it several times in the past. A colleague described him as 'a visionary who sees further into the future than anyone'. This is borne out by his decision - made 40 years ago - to study a one-millimetre long worm in detail to define the, biochemical and genetic control of its development and differentiation. The impact of these studies has been. so profound, with a significant bearing on human Physiology and disease, that over 400 laboratories worldwide have now adopted the worm as a research tool. In this article, a brief outline is given of his work on the worm and of some of the highlights of his brilliant career.
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