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Gregg L. Semenza
CELL (2012)
Expression of Prolyl Hydroxylases (PHDs) Is Selectively Controlled by HIF-1 and HIF-2 Proteins in Nucleus Pulposus Cells of the Intervertebral Disc DISTINCT ROLES OF PHD2 AND PHD3 PROTEINS IN CONTROLLING HIF-1α ACTIVITY IN HYPOXIA
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A large-scale replication study for the association of rs17039192 in HIF-2α with knee osteoarthritis
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Inhibition of Hypoxia-inducible Factor-targeting Prolyl Hydroxylase Domain-containing Protein 2 (PHD2) Enhances Matrix Synthesis by Human Chondrocytes
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B. Fermor et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes
C. T. Buckley et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
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Simon Stroebel et al.
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Regulation of Autophagy in Human and Murine Cartilage Hypoxia-Inducible Factor 2 Suppresses Chondrocyte Autophagy
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Increased collagen and aggrecan degradation with age in the joints of Timp3-/- mice
Solmaz Sahebjam et al.
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Placental but not heart defects are associated with elevated hypoxia-inducible factor α levels in mice lacking prolyl hydroxylase domain protein 2
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The effect of O2 tension on pH homeostasis in equine articular chondrocytes
P. J. Milner et al.
ARTHRITIS AND RHEUMATISM (2006)
The length of peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases
Peppi Koivunen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
SS Glasson et al.
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ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
H Stanton et al.
NATURE (2005)
Disease-modifying therapies for osteoarthritis - Current status
M Fajardo et al.
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Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1 alpha in articular chondrocytes: involvement of HIF-1 alpha in the pathogenesis of osteoarthritis
K Yudoh et al.
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Role of interleukin-1 and tumor necrosis factor a in matrix degradation of human osteoarthritic cartilage
M Kobayashi et al.
ARTHRITIS AND RHEUMATISM (2005)
Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes
G Martin et al.
ARTHRITIS AND RHEUMATISM (2004)
Control of human articular chondrocyte differentiation by reduced oxygen tension
CL Murphy et al.
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Oxygen sensing by HIF hydroxylases
CJ Schofield et al.
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TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors
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Redifferentiation of dedifferentiated bovine articular chondrocytes in alginate culture under low oxygen tension
C Domm et al.
OSTEOARTHRITIS AND CARTILAGE (2002)
Effect of oxygen tension and alginate encapsulation on restoration of the differentiated phenotype of passaged chondrocytes
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TISSUE ENGINEERING (2001)
Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice
LA Neuhold et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6
I Sekiya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)