Separation of cocaine stereoisomers by capillary electrophoresis using sulfated cyclodextrins

A capillary electrophoretic method for the separation of cocaine and its stereoisomers was developed. In this study, the effect of organic modifier was also investigated. The separation was achieved using 1% sulfated cyclodextrin, 10 mmol L-1 phosphate buffer, 10% methanol at pH 3. The method provides good reproducibility and easy application.