期刊
NEUROSCIENCE LETTERS
卷 341, 期 3, 页码 217-220出版社
ELSEVIER SCI IRELAND LTD
DOI: 10.1016/S0304-3940(03)00187-3
关键词
diphenyl diselenide; selenium; object recognition; memory; cognitive enhancers
Selenium compounds display antioxidant and neuroprotective properties. Diphenyl diselenide (PhSe)(2) is an organic selenium compound that affects a number of neuronal processes. The aim of the present study was to evaluate the effects of the systemic administration of (PhSe)(2) on novel object recognition memory in mice. Adult male CFI mice were given an i.p. injection of (PhSe)(2) (0.2, 1.0, 5.0, or 25.0 mumol/kg) 30 min before training in an object recognition task. (PhSe)2 did not affect short-term memory or the total time exploring both objects, but induced a facilitation of retention measured 24 h after training. The present findings show that systemic administration of (PhSe)(2) induces a facilitation of formation of long-term object recognition memory. (C) 2003 Published by Elsevier Science Ireland Ltd.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据