期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 1, 期 11, 页码 1833-1834出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b303113f
关键词
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The enantioselective synthesis of a potent Maxi-K potassium channel opener (BMS-204352) mediated by N-fluoroammonium salts of cinchona alkaloids is described. Two synthetic pathways were evaluated. An ee as high as 88% was achieved (> 99% after a single recrystallisation).
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