Stereoselective acylations of 1,2-azidoalcohols with vinyl acetate, catalyzed by lipase Amano PS

Lipase PS-catalyzed kinetic resolution of vicinal azidoalcohols was accomplished. The enzymatic reaction rates and the enantioselectivities were significantly enhanced under the ultrasonic irradiation. (C) 2003 Elsevier Science Ltd. All rights reserved.