期刊
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
卷 129, 期 1, 页码 53-59出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0166-6851(03)00093-8
关键词
Trypanosoma cruzi; tissue parasite burden; LightCycler; real-time PCR
资金
- NIAID NIH HHS [R01 AI33106, P01 AI44979] Funding Source: Medline
A real-time PCR technique that allows for accurate and sensitive quantitation of tissue parasite burden in animals infected with the protozoan parasite Trypanosoma cruzi. was developed. The utility of this method was demonstrated by confirmation of higher parasite load in mice with acute infections in comparision to chronically infected mice, detection of tissue-restricted parasite persistence in different parasite:host strain combinations, and the observation of increased tissue parasite burden with higher infective doses. This method should be a useful tool for monitoring parasite burden in hosts under various treatment regimens. (C) 2003 Elsevier Science B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据