期刊
JOURNAL OF ANTIBIOTICS
卷 56, 期 6, 页码 552-556出版社
JAPAN ANTIBIOT RES ASSN
DOI: 10.7164/antibiotics.56.552
关键词
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Liposidomycin, a potent inhibitor of bacterial peptidoglycan biosynthesis, represents the main component of a group of over 24 closely related, fatty acyl nucleoside antibiotics produced by Streptomyces. Exogeneously supplied myristic acid or palmitic acid resulted in the almost exclusive production of liposidomycin C-(III) and/or M-(III). Exogeneously supplied [1-C-13] -palmitic acid was incorporated directly into liposidomycin M-(III) as judged by the FAB-MS and C-13 NMR spectra.
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