期刊
ARQUIVOS BRASILEIROS DE OFTALMOLOGIA
卷 73, 期 5, 页码 409-413出版社
CONSEL BRASIL OFTALMOLOGIA
DOI: 10.1590/S0004-27492010000500004
关键词
Tomography, optical coherence; Perimetry; Optic atrophy; Optic chiasm; Hemianopsia; Visual fields
资金
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo FAPESP, Sao Paulo, Brazil [05/55326-1]
- Conselho Nacional de Desenvolvimento Cientfico e Tecnologico, CNPq, Brasilia, Brazil [309709/2007-5]
Purpose: To correlate visual field sensitivity (VFS) loss on standard automated perimetry (SAP) and quadrantic macular thickness on optical coherence tomography (OCT) in patients with permanent temporal hemianopia from chiasmal compression. Methods: Forty eyes from 40 patients with chiasmal compression and 40 healthy eyes were submitted to standard automated perimetry and Stratus-OCT scanning. Raw data of the fast macular thickness scanning protocol were exported and macular thickness measurements were recorded and averaged for each quadrant and half of the central area. The correlation between visual field sensitivity loss and optical coherence tomography measurements was tested with Pearson's correlation coefficients and with linear regression analysis. Results: A significant association was found between each macular thickness parameter and the corresponding central VF mean sensitivity. The strongest association was observed between superonasal macular thickness and the inferotemporal mean defect measured both in decibel (R=0.47; p=0.001) and in 1/Lambert (R=0.59; p<0.0001) units. Conclusion: Stratus-OCT-measured macular thickness was topographically related with visual field sensitivity loss in patients with temporal hemianopia from chiasmal compression. Such measurements could prove clinically useful in the diagnosis and follow-up of patients with chiasmal compression. ClinicalTrial.gov identifier number: NCT0039122.
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