期刊
NEUROPATHOLOGY
卷 23, 期 2, 页码 136-140出版社
BLACKWELL PUBLISHING ASIA
DOI: 10.1046/j.1440-1789.2003.00489.x
关键词
cadaveric dura mater graft; Creutzfeldt-Jakob disease; florid plaque; prion protein
A patient with dura-associated Creutzfeldt-Jakob disease (D-CJD) which occurred about 15 years after a dura mater graft is reported in the present study. The prion protein gene analysis disclosed no mutation. The D-CJD was atypical in: (i), the long interval between the onset of ataxia and the occurrence of dementia; (ii), the presence of transient myoclonus; and (iii), the presence of florid plaques in the brain. The electron-microscopic findings showed bundles of amyloid filaments which radiated from the center of the plaques without degenerating neurites. This case of D-CJD may belong to a new subtype of D-CJD.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据