Lower quality of life in longstanding mild primary hyperparathyroidism

Objective: To describe the non-classical manifestations and quality of life in patients with primary hyperparathyroidism (PHPT). Subjects and methods: We evaluated non-classical manifestations and quality of life of 22 patients with PHPT using the SF-36 questionnaire according to the time since diagnosis. Results: In the scores of quality of life, a significant difference was found comparing the groups with previous and recent diagnosis of PHPT in terms of functional capacity (39 + 22.83 vs. 76.25 + 22.37; p = 0.001), limitation of physical aspects (30 + 38.73 vs. 75 + 21.32; p = 0.006), general health (57.20 + 19.16 vs. 77.75 + 15.70; p = 0.012), and vitality (49.00 + 21.19 vs. 70.00 + 24.12; p = 0.044). Conclusion: We found a significant difference in quality of life in relation to the time of the diagnosis of PHPT. Arq Bras Endocrinol Metab. 2013; 57(2): 139-43