期刊
NEUROSCIENCE RESEARCH
卷 46, 期 2, 页码 229-240出版社
ELSEVIER SCI IRELAND LTD
DOI: 10.1016/S0168-0102(03)00062-2
关键词
fictive locomotion; respiratory rhythm; sympathetic rhythm; motor control; L-DOPA; opioids
During L-DOPA-induced fictive spinal locomotion rhythmic activities in nerves to internal intercostal and external oblique abdominal muscles and in phrenic and sympathetic nerves were observed which were always coordinated with locomotor activity in forelimb and hindlimb muscle nerves. A periodicity with longer lasting tonic phases could be induced by cutaneous nerve stimulation or asphyxia. This activity was observed in limb motor nerves as well as in respiratory motor and sympathetic nerves. A slow independent activity of the phrenic and intercostal nerves or the sympathetic nerves, which could be related to a normal respiratory rhythm or independent sympathetic rhythms was not observed. The findings indicate that during fictive spinal locomotion the activity of spinal rhythm generators for locomotion also projects onto respiratory and sympathetic spinal neurotics. (C) 2003 Elsevier Science Ireland Ltd and the Japan Neuroscience Society. All rights reserved.
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