期刊
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
卷 50, 期 6, 页码 649-656出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TBME.2003.812201
关键词
blood flow; one-dimensional analysis methods; simulation-based medical planning
Current practice in vascular surgery utilizes only diagnostic and empirical data to plan treatments and does not enable quantitative a priori prediction of the outcomes of interventions. We have previously described a new Approach to vascular surgery-planning based on solving the governing equations of blood flow in patient-specific models. A one-dimensional finite-element method was used to simulate blood flow in eight porcine thoraco-thoraco aortic bypass models. The predicted flow rate was compared to in vivo data obtained using cine phase-contrast magnetic resonance imaging. The mean absolute difference between computed and measured flow distribution in the stenosed aorta was found to be 4.2% with the maximum difference of. 10.6% and a minimum difference of 0.4%. Furthermore, the sensitivity of the, flow rate and distribution with respect to stenosis and branch losses were quantified.
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