期刊
BIOCHEMICAL SOCIETY TRANSACTIONS
卷 31, 期 -, 页码 648-651出版社
PORTLAND PRESS
DOI: 10.1042/BST0310648
关键词
bacterial infection; fruit fly; innate immunity; signal transduction
资金
- NIAID NIH HHS [1P01 AI44220] Funding Source: Medline
The Drosophila Toll receptor controls the immune response to Gram-positive bacteria and fungi by activating a signalling pathway partially conserved throughout evolution. The Drosophila genome encodes eight additional Toll-related receptors, most of which appear to carry out developmental rather than immune functions. one exception may be Toll-9, which shares structural and functional similarities with mammalian TLRs.
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