期刊
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
卷 27, 期 6-7, 页码 465-497出版社
ELSEVIER SCI LTD
DOI: 10.1016/S0145-305X(03)00027-2
关键词
mouse; IMGT; T cell receptor alpha; T cell receptor delta; variable gene
'The Mouse (Mus musculus) T cell receptor alpha (TRA) and delta (TRD) variable genes' 'IMGT Locus in Focus' report provides the first complete list of the mouse TRAV and TRDV genes which span 1550 kb on chromosome 14 at 19.7 cM. The total number of TRAV genes per haploid genome is 98 belonging to 23 subgroups. This includes 10 TRAV/DV genes which belong to seven subgroups. The functional TRAV genomic repertoire comprises 72-82 TRAV (including 9-10 TRAV/DV) belonging to 19 subgroups. The total number of TRDV genes per haploid genome is 16 (including the 10 TRAV/DV) belonging to 12 subgroups. The functional TRDV genomic repertoire comprises 14-15 genes (5 TRDV and 9-10 TRAV/DV) belonging to 11-12 subgroups. The eight tables and three figures of this report are available at the IMGT Marie-Paule page of IMGT. The international ImMunoGeneTics information system(R) (http://imgt.cines.fr) created by Marie-Paule Lefranc, Universite Montpellier II, CNRS, France. (C) 2003 Elsevier Science Ltd. All rights reserved.
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