期刊
ADVANCED MATERIALS
卷 15, 期 11, 页码 888-+出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200304621
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Synthetic biomaterial matrices have been formed in the presence of cells by a Michael-type addition reaction between a difunctional protease substrate peptide, a monofunctional cell adhesion peptide, and a tetrafunctional poly(ethylene glycol). These materials locally degrade in response to cell-surface proteases, allowing cells to create paths for 3D cell migration (see Figure).
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