期刊
MICROBES AND INFECTION
卷 5, 期 8, 页码 723-730出版社
ELSEVIER
DOI: 10.1016/S1286-4579(03)00114-X
关键词
mucosal immunity; Th1-th2 response; cytokines; Helicobacter pvtori; chronic gastritis; peptic ulcer; gastric cancer; gastric lymphoma
Host T-cell response to Helicobacter pylori is important for the clinical outcome of the infection. A Th1-polarized response, preferentially against Ca-A. is associated with peptic ulcer, whereas mixed Th1 and Th0 responses are present in non-ulcer gastritis. A deregulated H. pylori-driven Th0 cell-dependent B-cell activation is found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
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