期刊
JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT
卷 40, 期 4, 页码 63-69出版社
JOURNAL REHAB RES & DEV
DOI: 10.1682/JRRD.2003.08.0063
关键词
animal models; behavior; electrophysiology; human spinal cord injury (SCI); neuropathology; neuroprotection; outcome measures; replication studies; safety; spinal cord trauma; transplantation
资金
- NINDS NIH HHS [R01 NS42133, 1PO1 NS38665, 5P50 NS30291] Funding Source: Medline
As the spinal cord injury (SCI) scientific community moves closer to translating experimental data to the clinic, specific steps should be addressed to improve our chances of success. Some of the steps under discussion include animal modeling, clinically relevant endpoints, compelling evidence for improvements, and safety issues. First, it will be beneficial if exciting data are first replicated before findings are considered clinically relevant. Then major findings must be published in peer-reviewed journals so that the scientific community may scrutinize the data. Finally, continued communication between different research groups throughout the world, as well as between basic scientists and clinicians working in the area of SCI, will enhance our progress in this important research field.
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