期刊
JOURNAL OF ANTIBIOTICS
卷 56, 期 7, 页码 639-646出版社
JAPAN ANTIBIOT RES ASSN
DOI: 10.7164/antibiotics.56.639
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A new secondary metabolite was detected in the culture extract of Streptomyces sp. AK 409 by HPLC-diode-array screening. The metabolite was identified as pyrocoll, which is known to be a constituent of cigarette smoke. Pyrocoll is known as a synthetic compound, but until now had not been isolated as a natural product from a microorganism. The compound showed biological activity against various Arthrobacter strains, filamentous fungi, several pathogenic protozoa, and some human tumor cell lines.
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