期刊
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
卷 27, 期 4, 页码 267-281出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0895-6111(02)00093-9
关键词
image registration; mutual information; thin plate spline; prostate cancer therapy; interventional magnetic resonance imaging
资金
- NCI NIH HHS [R01-CA84433-01, R33-CA88144-01, R01 CA084433] Funding Source: Medline
A three-dimensional warping registration algorithm was created and compared to rigid body registration of magnetic resonance (MR) pelvic volumes including the prostate. The rigid body registration method combines the advantages of mutual information (MI) and correlation coefficient at different resolutions. Warping registration is based upon independent optimization of many interactively placed control points (CP's) using MI and a thin plate spline transformation. More than 100 registration experiments with 17 MR volume pairs determined the quality of registration under conditions simulating potential interventional MRI-guided treatments of prostate cancer. For image pairs that stress rigid body registration (e.g. supine, the diagnostic position, and legs raised, the treatment position), both visual and numerical evaluation methods showed that warping consistently worked better than rigid body. Experiments showed that approximate to 180 strategically placed CP's were sufficiently expressive to capture important features of the deformation. (C) 2002 Elsevier Science Ltd. All rights reserved.
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