期刊
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
卷 189, 期 1, 页码 239-244出版社
MOSBY-ELSEVIER
DOI: 10.1067/mob.2003.441
关键词
overweight; obesity; pregnancy; gestational diabetes mellitus; oral glucose tolerance test; maternal-fetal outcome; pregnancy weight gain
OBJECTIVE: This study was undertaken to investigate the relationship between pregnancy outcome and prepregnancy overweight or obesity in women with a normal glucose tolerance test. STUDY DESIGN: A historical cohort study of 2459 pregnant women systematically examined for gestational diabetes was performed. Information of oral glucose tolerance test results and clinical outcome were collected from medical records. RESULTS: The risk of hypertensive complications, cesarean section, induction of labor and macrosomia was significantly increased in both overweight women (body mass index [BMI] 25.0-29.9 kg/m(2)) and obese women (BMI greater than or equal to 30.0 kg/m(2)) compared with women who were of normal weight (BMI 18.5-24.9 kg/m(2)). The frequencies of shoulder dystocia, preterm delivery, and infant morbidity other than macrosomia were not significantly associated with maternal BMI. CONCLUSION: Prepregnancy overweight and obesity is associated with adverse pregnancy outcome in glucose-tolerant women.
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