期刊
ARCHIVES OF PHARMACAL RESEARCH
卷 26, 期 7, 页码 532-534出版社
PHARMACEUTICAL SOCIETY KOREA
DOI: 10.1007/BF02976876
关键词
marine fungus; Altenaria sp.; kojic acid; kojic acid methyl ether; phomaligol; tyrosinase; inhibitory
Kojic acid dimethyl ether (1), and the known kojic acid monomethyl ether (2), kojic acid (3) and phomaligol A (4) have been isolated from the organic extract of the broth of the marine-derived fungus Altenaria sp. collected from the surface of the marine green alga Ulva pertusa. The structures were assigned on the basis of comprehensive spectroscopic analyses. Each isolate was tested for its tyrosinase inhibitory activity. Kojic acid (3) was found to have significant tyrosinase inhibitory activity, but compounds 1, 2, and 4 were found to be inactive.
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