期刊
PEDIATRIC CARDIOLOGY
卷 24, 期 4, 页码 369-374出版社
SPRINGER
DOI: 10.1007/s00246-002-0335-9
关键词
congenital heart disease; cleft lip; cleft palate; Doppler echocardiogram
To establish the prevalence of congenital heart diseases (CHDs) in cleft patients, the type of cleft and the presence of a syndrome were coded in 220 patients. A Doppler echocardiogram with color-flow mapping (DE) was obtained in all patients. Mean age was 112.0 +/- 101.2 months (range, 1-576 months), and 56.8% (125) were males. Cleft lip and palate occurred in 144 patients (65.5%), cleft lip in 40 (18.2%). and cleft palate in 36 (16.4%). Cleft palates were more frequent among females. Twenty-four CHDs were diagnosed in 21 of 220 patients (9.5%): 7 mitral valve prolapses, 6 atrial septal defects, 4 patent ductus arteriosus, 3 ventricular septal defects, 2 cases of tetralogy of Fallot, 1 pulmonary stenosis, and 1 bicuspid aortic valve. The presence of CHD did not correlate with the type of clef. Syndromes occurred in 28 patients (12.7%), and this association was higher among patients with a cleft palate.
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