期刊
NUCLEIC ACIDS RESEARCH
卷 31, 期 13, 页码 3789-3791出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkg620
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资金
- NIGMS NIH HHS [R01 GM063029, R01-GM63029-01] Funding Source: Medline
- NLM NIH HHS [R01 LM007329, 1-R01-LM07329-01] Funding Source: Medline
UniqueProt is a practical and easy to use web service designed to create representative, unbiased data sets of protein sequences. The largest possible representative sets are found through a simple greedy algorithm using the HSSP-value to establish sequence similarity. UniqueProt is not a real clustering program in the sense that the 'representatives' are not at the centres of well-defined clusters since the definition of such clusters is problem-specific. Overall, UniqueProt is a reasonable fast solution for bias in data sets. The service is accessible at http://cubic.bioc.columbia.edu/services/uniqueprot; a command-line version for Linux is downloadable from this web site.
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