期刊
INFECTION AND IMMUNITY
卷 71, 期 7, 页码 4206-4211出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.71.7.4206-4211.2003
关键词
-
资金
- NIAID NIH HHS [AI43356, R01 AI043356] Funding Source: Medline
Mutation of sarA resulted in a reduced capacity to form a biofilm in six of the eight Staphylococcus aureus strains we tested (UAMS-1, UAMS-601, SA113, SC-01, S6C, and DB). The exceptions were Newman, which formed a poor biofilm under all conditions, and RN6390, which consistently formed a biofilm only after mutation of agr. Mutation of agr in other strains had little impact on biofilm formation. In every strain other than Newman, including RN6390, simultaneous mutation of sarA and agr resulted in a phenotype like that observed with the sarA mutants. Complementation studies using a sarA clone confirmed that the defect in biofilm formation was due to the sarA mutation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据