期刊
ARCHIVES OF VIROLOGY
卷 157, 期 12, 页码 2349-2355出版社
SPRINGER WIEN
DOI: 10.1007/s00705-012-1410-z
关键词
Bat coronavirus; Coronavirus; Bats; Antibody; Viruses; SARS; Severe acute respiratory syndrome; Zoonosis
类别
资金
- Ministry of Education, Culture, Sports, Science and Technology, Japan
- Grants-in-Aid for Scientific Research [23658252, 22405039, 21406012] Funding Source: KAKEN
Bat coronavirus (BtCoV) is assumed to be a progenitor of severe acute respiratory syndrome (SARS)-related coronaviruses. To explore the distribution of BtCoVs in the Philippines, we collected 179 bats and detected viral RNA from intestinal or fecal samples by RT-PCR. The overall prevalence of BtCoVs among bats was 29.6 %. Phylogenetic analysis of the partial RNA-dependent RNA polymerase gene suggested that one of the detected BtCoVs was a novel alphacoronavirus, while the others belonged to the genus Betacoronavirus. Western blotting revealed that 66.5 % of bat sera had antibodies to BtCoV. These surveys suggested the endemic presence of BtCoVs in the Philippines.
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