相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis
Seddik Hammad et al.
ARCHIVES OF TOXICOLOGY (2014)
A theoretical study of lipid accumulation in the liver-implications for nonalcoholic fatty liver disease
J. Schleicher et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2014)
Integrated Metabolic Spatial-Temporal Model for the Prediction of Ammonia Detoxification During Liver Damage and Regeneration
Freimut Schliess et al.
HEPATOLOGY (2014)
How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis
Dirk Drasdo et al.
JOURNAL OF HEPATOLOGY (2014)
A Novel Mitochondrial MAVS/Caspase-8 Platform Links RNA Virus-Induced Innate Antiviral Signaling to Bax/Bak-Independent Apoptosis
Souhayla El Maadidi et al.
JOURNAL OF IMMUNOLOGY (2014)
Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis
Bi-Sen Ding et al.
NATURE (2014)
Endothelial Cell-Derived Angiopoietin-2 Controls Liver Regeneration as a Spatiotemporal Rheostat
Junhao Hu et al.
SCIENCE (2014)
A Multi-Scale Model of Hepcidin Promoter Regulation Reveals Factors Controlling Systemic Iron Homeostasis
Guillem Casanovas et al.
PLOS COMPUTATIONAL BIOLOGY (2014)
Spatio-Temporal Simulation of First Pass Drug Perfusion in the Liver
Lars Ole Schwen et al.
PLOS COMPUTATIONAL BIOLOGY (2014)
Clinical Translation in the Virtual Liver Network
L. Kuepfer et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2014)
Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes
Markus Schug et al.
ARCHIVES OF TOXICOLOGY (2013)
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
Patricio Godoy et al.
ARCHIVES OF TOXICOLOGY (2013)
Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK
A. Geissler et al.
CELL DEATH AND DIFFERENTIATION (2013)
A community-driven global reconstruction of human metabolism
Ines Thiele et al.
NATURE BIOTECHNOLOGY (2013)
ABCC11/MRP8 polymorphisms affect 5-fluorouracil-induced severe toxicity and hepatic expression
Tarek Magdy et al.
PHARMACOGENOMICS (2013)
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
Ulrich M. Zanger et al.
PHARMACOLOGY & THERAPEUTICS (2013)
Direct Transcriptional Regulation of Human Hepatic Cytochrome P450 3A4 (CYP3A4) by Peroxisome Proliferator-Activated Receptor Alpha (PPARα)
Maria Thomas et al.
MOLECULAR PHARMACOLOGY (2013)
The extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes
Sebastian Vlaic et al.
BMC SYSTEMS BIOLOGY (2012)
In Vitro - In Vivo Correlation of Gene Expression Alterations Induced by Liver Carcinogens
T. Heise et al.
CURRENT MEDICINAL CHEMISTRY (2012)
A methionine-choline-deficient diet elicits NASH in the immunodeficient mouse featuring a model for hepatic cell transplantation
Sandra Pelz et al.
EXPERIMENTAL CELL RESEARCH (2012)
An integrative model links multiple inputs and signaling pathways to the onset of DNA synthesis in hepatocytes
Jeremy Huard et al.
FEBS JOURNAL (2012)
Kinetic Modeling of Human Hepatic Glucose Metabolism in Type 2 Diabetes Mellitus Predicts Higher Risk of Hypoglycemic Events in Rigorous Insulin Therapy
Matthias Koenig et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Rab5 is necessary for the biogenesis of the endolysosomal system in vivo
Anja Zeigerer et al.
NATURE (2012)
Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis
Joanna D. Stewart et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Quantifying the Contribution of the Liver to Glucose Homeostasis: A Detailed Kinetic Model of Human Hepatic Glucose Metabolism
Matthias Koenig et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
Integrating Cellular Metabolism into a Multiscale Whole-Body Model
Markus Krauss et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
Mechanistic, Model-Based Approach to Safety Assessment in Clinical Development
J. Lippert et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2012)
A physiologically based toxicokinetic modelling approach to predict relevant concentrations for in vitro testing
Hans Mielke et al.
ARCHIVES OF TOXICOLOGY (2011)
A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes
Joachim Bucher et al.
BMC SYSTEMS BIOLOGY (2011)
Distinct Functions of the Mitogen-activated Protein Kinase-activated Protein (MAPKAP) Kinases MK2 and MK3 MK2 MEDIATES LIPOPOLYSACCHARIDE-INDUCED SIGNAL TRANSDUCERS AND ACTIVATORS OF TRANSCRIPTION 3 (STAT3) ACTIVATION BY PREVENTING NEGATIVE REGULATORY EFFECTS OF MK3
Christian Ehlting et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression
Katarzyna Mleczko-Sanecka et al.
BLOOD (2010)
Transcription Factors ETF, E2F, and SP-1 Are Involved in Cytokine-Independent Proliferation of Murine Hepatocytes
Sebastian Zellmer et al.
HEPATOLOGY (2010)
HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology
Christoph Gille et al.
MOLECULAR SYSTEMS BIOLOGY (2010)
Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration
Bi-Sen Ding et al.
NATURE (2010)
Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration
Stefan Hoehme et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts
Nils Bluethgen et al.
FEBS JOURNAL (2009)
Hepatocyte-specific Smad7 expression attenuates TGF-β-mediated fibrogenesis and protects against liver damage
Steven Dooley et al.
GASTROENTEROLOGY (2008)
Switch from Type II to I Fas/CD95 Death Signaling on In Vitro Culturing of Primary Hepatocytes
Dorothee Walter et al.
HEPATOLOGY (2008)
Mathematical modelling of liver regeneration after intoxication with CCl4
Stefan Hoehme et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2007)
分享论文
