期刊
SCIENCE
卷 301, 期 5631, 页码 336-338出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1085242
关键词
-
资金
- NIAID NIH HHS [AI43288] Funding Source: Medline
- NIGMS NIH HHS [GM34028] Funding Source: Medline
Small RNAs, including microRNAs (miRNAs) and short interfering RNAs (siRNAs), are key components of an evolutionarily conserved system of RNA-based gene regulation in eukaryotes. They are involved in many molecular interactions, including defense against viruses and regulation of gene expression during development. miRNAs interfere with expression of messenger RNAs encoding factors that control developmental timing, stem cell maintenance, and other developmental and physiological processes in plants and animals. miRNAs are negative regulators that function as specificity determinants, or guides, within complexes that inhibit protein synthesis (animals) or promote degradation (plants) of mRNA targets.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据