相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation
Mitchell R. McGill et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
On-line HPLC Analysis System for Metabolism and Inhibition Studies in Precision-Cut Liver Slices
Paul M. van Midwoud et al.
ANALYTICAL CHEMISTRY (2011)
1-Aminobenzotriazole, a Known Cytochrome P450 Inhibitor, Is a Substrate and Inhibitor of N-Acetyltransferase
Q. Sun et al.
DRUG METABOLISM AND DISPOSITION (2011)
HepaRG Cells: A Human Model to Study Mechanisms of Acetaminophen Hepatotoxicity
Mitchell R. McGill et al.
HEPATOLOGY (2011)
Gene expression analysis of precision-cut human liver slices indicates stable expression of ADME-Tox related genes
M. G. L. Elferink et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2011)
Role of Human Glutathione S-Transferases in the Inactivation of Reactive Metabolites of Clozapine
Sanja Dragovic et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2010)
Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies
Inge A. M. de Graaf et al.
NATURE PROTOCOLS (2010)
Differential Regulation of Mitogen-Activated Protein Kinase Pathways by Acetaminophen and Its Nonhepatotoxic Regioisomer 3′-Hydroxyacetanilide in TAMH Cells
Brendan D. Stamper et al.
TOXICOLOGICAL SCIENCES (2010)
Acetaminophen overdose with altered acetaminophen pharmacokinetics and hepatotoxicity associated with premature cessation of intravenous N-acetylcysteine therapy
Silas W. Smith et al.
ANNALS OF PHARMACOTHERAPY (2008)
Mechanistic Investigation of the Noncytochrome P450-Mediated Metabolism of Triadimefon to Triadimenol in Hepatic Microsomes
John F. Kenneke et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2008)
The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system
Ian M. Copple et al.
HEPATOLOGY (2008)
Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity
M. G. L. Elferink et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2008)
Interspecies differences in acetaminophen sensitivity of human, rat, and mouse primary hepatocytes
Katalin Jemnitz et al.
TOXICOLOGY IN VITRO (2008)
Precision-cut tissue slices as a tool to predict metabolism of novel drugs
Inge A. M. de Graaf et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2007)
Standardized peptidome profiling of human urine by magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Georg Martin Fiedler et al.
CLINICAL CHEMISTRY (2007)
Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice
CEP Goldring et al.
HEPATOLOGY (2004)
Organ slices for the evaluation of human drug toxicity
AEM Vickers et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2004)
Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats:: Possible implications for toxicogenomics use of in vitro systems
F Boess et al.
TOXICOLOGICAL SCIENCES (2003)
Identification of metabolic pathways involved in the biotransformation of tolperisone by human microsomal enzymes
B Dalmadi et al.
DRUG METABOLISM AND DISPOSITION (2003)
Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice
C Ju et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2002)
Comparison of in vitro preparations for semi-quantitative prediction of in vivo drug metabolism
IAM De Graaf et al.
DRUG METABOLISM AND DISPOSITION (2002)
Role of ATP and glycogen reserves in both paracetamol sulfation and glucuronidation by cultured precision-cut rat liver slices
E Evdokimova et al.
TOXICOLOGY IN VITRO (2001)
Precision-cut liver slices: characteristics and use for in vitro pharmaco-toxicology
C Lerche-Langrand et al.
TOXICOLOGY (2000)
Concordance of the toxicity of pharmaceuticals in humans and in animals
H Olson et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2000)
分享论文
