期刊
JOURNAL OF MEDICAL MICROBIOLOGY
卷 52, 期 8, 页码 721-726出版社
MICROBIOLOGY SOC
DOI: 10.1099/jmm.0.04845-0
关键词
-
类别
The relationship between chronic Chlamydophila (formerly Chlamydia) pneumoniae infection and lung carcinoma was investigated. A total of 123 patients who were smokers and diagnosed with lung carcinoma based on clinical and laboratory (radiological, cytological) findings were examined. Of these patients, 70 had small-cell, 28 squamous-cell and seven large-cell carcinomas, while 18 had adenocarcinoma. A total of 123 healthy persons matching patients in age, sex, duration of smoking and locality were chosen as controls. Blood samples (5 ml) were withdrawn at the time of diagnosis and 1 month later. The values between IgG greater than or equal to 512 and IgA greater than or equal to 40 were set as the criteria for chronic Chlamydophila pneumoniae infections. In male patients with lung carcinoma, Chlamydophila pneumoniae IgG antibody titres of greater than or equal to 512 and IgA antibody titres of greater than or equal to 40 were found at a higher rate than in the control group. This ratio was not significant for the female patients. In chronic Chlamydophila pneumoniae infections, Chlamydophila pneumoniae antibody titres with values IgG greater than or equal to 512 and IgA greater than or equal to 40 were found in a total of 62 (50(.)4 %) cases. Chronic Chlamydophila pneumoniae infections were seen statistically more often in male patients with carcinoma who were aged 55 years or younger. This study supports the idea that chronic Chlamydophila pneumoniae infection increases the risk of lung carcinoma.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据