期刊
NATURE CELL BIOLOGY
卷 5, 期 8, 页码 684-688出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ncb0803-684
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Cholesterol is a structural component of animal membranes that influences fluidity, permeability and formation of lipid microdomains. It is also a precursor to signalling molecules, including mammalian steroid hormones and insect ecdysones. The nematode Caenorhabditis elegans requires too little cholesterol for it to have a major role in membrane structure. Instead, its most probable signalling functions are to control molting and induce a specialized non-feeding larval stage, although no cholesterol-derived signalling molecule has yet been identified for these or any other functions.
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